Understanding Aging, Fatigue, and Inflammation: When the Immune System and Brain Compete for Energy in the Body (Original Publisher)

As populations age and chronic fatigue becomes more prevalent across medical conditions, understanding the biological roots of energy imbalance is more important than ever. Understanding Aging, Fatigue, and Inflammation: When the Immune System and Brain Compete for Energy in the Body presents a cutting-edge, integrative perspective on how the body prioritizes energy between the immune system and the brain—and how this dynamic contributes to fatigue, cognitive changes, and inflammatory disorders.

This scientifically grounded yet accessible book explores the complex interplay between neuroinflammation, immune activation, and mitochondrial function. It’s a must-read for professionals in gerontology, immunology, neurology, psychiatry, and internal medicine—as well as for students, researchers, and clinicians focused on chronic fatigue, aging, or inflammation-related diseases.

Key Features and Highlights:

• Energy Allocation Framework: Introduces a novel framework showing how competition between the immune system and brain for energy leads to fatigue and cognitive decline.
• Multidisciplinary Insights: Bridges neuroscience, immunology, endocrinology, and metabolism to offer a unified view of aging and systemic inflammation.
• Clinical Relevance: Explores fatigue in chronic illnesses like ME/CFS, depression, autoimmune diseases, and long COVID.
• Up-to-Date Research: Includes the latest findings from 2024 on mitochondrial dysfunction, neuroimmune interactions, and aging biomarkers.
• Evidence-Based and Practical: Highlights implications for clinical care, early detection, and potential therapeutic targets.

Chapters and Topics Covered:
Includes core chapters on:

• The biology of energy production and allocation
• Immune system activation and its metabolic costs
• Neuroinflammation and brain energy metabolism
• Mechanisms of fatigue in chronic disease and aging
• Interventions to improve energy balance and reduce inflammation

About the Author:
Authored by renowned researchers in immunometabolism and neuroscience, the contributors are leaders in exploring the intersection of energy metabolism, chronic disease, and aging-related fatigue.

Technical Details:

• Format:  PDF
• File Size: Approx. 6–8 MB
• Language: English
• Device Compatibility: Readable on all major platforms, including tablets, smartphones, laptops, and eReaders (Kindle, Kobo, iBooks, etc.)

Frequently Asked Questions (FAQs)

Q1: Is this book suitable for clinical practitioners or only for researchers?
A1: This book is ideal for both. While grounded in rigorous science, it offers clinically relevant insights that practitioners in neurology, geriatrics, internal medicine, and psychiatry can apply to patient care.

Q2: Does this book address chronic fatigue syndromes and their biological basis?
A2: Yes, the book discusses chronic fatigue, including conditions like ME/CFS and post-viral fatigue (such as long COVID), within the context of energy imbalance between the brain and immune system.